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CFT7455
CAS No. : 2504235-67-8
Biological Activity:CFT7455 is an orally active zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3) degrader. CFT7455 is an anti-cancer agent that binds with high affinity to the cereblon E3 ligase (Kd of 0.9 nM) (WO2022032132A1; Compound 1).
Research Area:Cancer
Targets:Ligands for E3 Ligase
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Cancer Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Ubiquitination Compound Library;Orally Active Compound Library;Anti-Blood Cancer Compound Library;Transcription Factor-Targeted Library;E3 Ligase Ligand Library;
Related Small Molecules:(S,R,S)-AHPC TFA;CRBN modulator-1;cIAP1 ligand 4;(S,R,S)-AHPC-Me;cIAP1 ligand 2;E3 ligase Ligand 23;VH032;BC-1215;VH032-cyclopropane-F;KB02-COOH;N-Boc-SBP-0636457-OH;SJPYT-195;TD-106;CC-885;VH032-OH
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