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Hypaconitine
CAS No. : 6900-87-4
Biological Activity：Hypaconitine, an active and highly toxic constituent derived from Aconitum species, is widely used to treat rheumatism.
IC50 value:
Target:
In vitro: The present study investigated the metabolism of hypaconitine in vitro using male human liver microsomes. The primary contributors toward HA metabolism were CYP3A4 and 3A5, with secondary contributions by CYP2C19, 2D6 and CYP2E1 [1].
In vivo:
Research Area：Inflammation/Immunology
Targets：TNF Receptor
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