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D[LEU4,LYS8]-VP TFA
Biological Activity:D[LEU4,LYS8]-VP TFA is a selective agonist of vasopressin V1b receptor, with the Kis of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V1b receptor, respectively. D[LEU4,LYS8]-VP TFA has weak antidiuretic, vasopressor, and in vitro oxytocic activities[2].
Research Area:Neurological Disease|Cardiovascular Disease
Targets:Vasopressin Receptor
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Macrocyclic Compound Library;Anti-Cardiovascular Disease Compound Library;Peptide Library;Cyclic Peptide Library;
Related Small Molecules:Lixivaptan;Mozavaptan hydrochloride;Balovaptan;Big Endothelin-1 (1-38), human;WAY-151932;Felypressin;Antagonist G TFA;Mozavaptan-d6;SKF 100398;Fedovapagon;L-371,257;Argipressin;D[LEU4,LYS8]-VP;d[Cha4]-AVP;RG7713;TASP0390325;Terlipressin-d5;SRX246;Terlipressin acetate;SR 49059;Big Endothelin-1 (1-39), porcine
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