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Piromelatine
CAS No. : 946846-83-9
Biological Activity:Piromelatine (Neu-P11) is a melatonin MT1/MT2 receptor agonist, serotonin 5-HT1A/5-HT1D agonist, and serotonin 5-HT2B antagonist. Piromelatine (Neu-P11) possesses sleep promoting, analgesic, anti-neurodegenerative, anxiolytic and antidepressant potentials. Piromelatine (Neu-P11) also possesses pain-related P2X3, TRPV1, and Nav1.7 channel-inhibition capacities[2][3].
Research Area:Neurological Disease
Targets:5-HT Receptor|Melatonin Receptor|TRP Channel|Sodium Channel|P2X Receptor
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Neurotransmitter Receptor Compound Library;Anti-Alzheimer’s Disease Compound Library;Neuroprotective Compound Library;Mechanoreceptors Compound Library;Antidepressant Compound Library;Sodium Channel Blocker Library;5-HT Receptor Compound Library;Human Metabolite Library;Coagulation and Anti-coagulation Compound Library;
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