For research use only. We do not sell to patients.
Hydrochlorothiazide
CAS No. : 58-93-5
Biological Activity:Hydrochlorothiazide (HCTZ), an orally active diuretic drug of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[2][3].
Research Area:Metabolic Disease|Cardiovascular Disease|Cancer
Targets:Potassium Channel|TGF-beta/Smad
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;Bioactive Compound Library Plus;Peptidomimetic Library;
Related Small Molecules:TGFβ-IN-2;Kv3 modulator 2;Brompheniramine-d6 maleate;Pinacidil;AMP-PNP tetralithium;IK1 inhibitor PA-6;VU590;Domiphen bromide;Mesoridazine benzenesulfonate;Tetrandrine;20(S)-Ginsenoside Rg3;(S)-(+)-Modafinic acid-d5;Ketanserin;PE 22-28;Ifenprodil tartrate;Brompheniramine maleate;L-Palmitoylcarnitine-d3 hydrochloride;Phe-Met-Arg-Phe amide trifluoroacetate;Mitiglinide;Flupirtine-d4 hydrochloride;SRI-011381;Ponsegromab;Kaliotoxin (1-37)
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use;
- Structurally and synthetically diverse biologically active compounds;
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.;
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.;
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.;
- Customized order volume ranging from milligrams to kilograms scale;
Structurally and synthetically diverse biologically active compounds;
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.