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Feprazone
CAS No. : 30748-29-9
Biological Activity：Feprazone (DA2370; Prenazone), an analogue of Phenylbutazone (HY-B0230), is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic activities. Feprazone acts by inhibiting the activity of cyclooxygenase (COX)-2. Feprazone ameliorates free fatty acid (FFA)-induced oxidative stress by reducing the production of mitochondrial reactive oxygen species (ROS). Feprazone can decrease the expression of MMP-2 and MMP-9. Besides, Feprazone can suppress adipogenesis and increase lipolysis in differentiating 3 T3-L1 cells. Feprazone also can be used to research atherosclerosis and obesity[2][3].
Research Area：Inflammation/Immunology
Targets：Reactive Oxygen Species|MMP|COX
Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Akt/NF-κB/JNK-IN-1;Chitoheptaose heptahydrochloride;COX-2/5-LOX-IN-3;N-Acetyl-D-cysteine;Topoisomerase I/II inhibitor 3;CYPMPO;Antioxidant agent-5;WAY-170523;CTTHWGFTLC, CYCLIC;ROS-ERS inducer 1;Ampyrone;Edaravone;Glucosamine-13C hydrochloride;COX-2-IN-24;L-Ascorbic acid sodium salt;D-Isofloridoside;L-Carnitine-d3 hydrochloride;Licochalcone D;Zaltoprofen-d7;Euparin;RH-EDA;1,3-Dicaffeoylquinic acid;α-Vitamin E-d6;1-Hydroxy-ibuprofen;Antitumor agent-68;Echinocystic acid;Glucosamine-13C6,15N hydrochloride;PI3Kα-IN-8
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