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Vincamine
CAS No. : 1617-90-9
Biological Activity：Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation. Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research[2].
Research Area：Metabolic Disease|Cardiovascular Disease
Targets：Free Fatty Acid Receptor
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Related Small Molecules:GW-1100;Grifolic acid;Ginsenoside Rb2;AP5;GPR40 Activator 1;AM-1638;DC260126;TUG-770;LY2881835;FFA1 agonist-1;GPR120 Agonist 3;AS2034178 free base;GPR40 Agonist 2;BMS-986118;AMG7703;Fasiglifam;MEDICA16;AR420626;AMG 837 sodium salt;Xelaglifam;TUG-1375;GPR120 Agonist 1;GPR40 agonist 5;TUG-424;GPR120 modulator 2;LY2922470;4-CMTB
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