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Desmorpholinyl Quizartinib-PEG2-COOH

CAS No. : 2292116-14-2

Biological Activity：Desmorpholinyl Quizartinib-PEG2-COOH incorporates a ligand for FLT-3, and a PEG-based PROTAC linker. Desmorpholinyl Quizartinib-PEG2-COOH can be used in the synthesis of PROTAC FLT-3 degrader 1 (HY-114323). PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC₅₀ 0.6 nM.

Research Area：Cancer

Targets：Target Protein Ligand-Linker Conjugates

Related Small Molecules:K-Ras ligand-Linker Conjugate 3;K-Ras ligand-Linker Conjugate 1;BMS-1166-N-piperidine-CO-N-piperazine;MRTX849 ethoxypropanoic acid;K-Ras ligand-Linker Conjugate 6;BRD4 ligand-Linker Conjugate 1;Ahx-DM1 TFA;K-Ras ligand-Linker Conjugate 2;K-Ras ligand-Linker Conjugate 5;K-Ras ligand-Linker Conjugate 4;(Rac)-PROTAC PARP/EGFR ligand 1;ERRα Ligand-Linker Conjugates 1;FAK ligand-Linker Conjugate 1

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

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