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Colivelin TFA
Biological Activity：Colivelin TFA is a brain penetrant neuroprotective peptide and a potent activator of STAT3, suppresses neuronal death by activating STAT3 in vitro. Colivelin TFA exhibits long-term beneficial effects against neurotoxicity, Aβ deposition, neuronal apoptosis, and synaptic plasticity deficits in neurodegenerative disease[2]. Colivelin TFA has the potential for the treatment of alzheimer’s disease and ischemic brain injury.
Research Area：Neurological Disease
Targets：STAT|Amyloid-β|Apoptosis
Related Screening Libraries:Bioactive Compound Library Plus;Peptide Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;β-Amyloid (13-27);Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Saikosaponin C;BJE6-106;Dinaciclib;Cirsilineol;Ecteinascidin 770;MDM2-p53-IN-15;Ochromycinone;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9
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Structurally and synthetically diverse biologically active compounds；
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