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GS-441524
CAS No. : 1191237-69-0
Biological Activity:GS-441524, predominant metabolite of Remdesivir and superior to Remdesivir against Covid-19 , shows comparable efficacy in cell-based models of primary human lung and cat cells infected with coronavirus. GS-441524 could strongly inhibits feline infectious peritonitis virus (FIPV), with an EC50 of 0.78 μM[2][3].
Research Area:Infection
Targets:DNA/RNA Synthesis|SARS-CoV
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Cell Cycle/DNA Damage Compound Library;Clinical Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;
Related Small Molecules:Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;P1788;SARS-CoV-2-IN-33;Thymidine-13C5,15N;NSC 617145;GRL-0496;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Antitumor agent-74;Grazoprevir potassium salt;Risdiplam;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;TH287 hydrochloride
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