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Vobramitamab duocarmazine
CAS No. : 2490556-51-7
Biological Activity：Vobramitamab duocarmazine (AEX4089DC1; MGC018), a humanized antibody-drug conjugate (ADC) (Antibody-Drug Conjugates (ADCs)) targeted against B7-H3 (CD276). Vobramitamab duocarmazine is comprised of the cleavable linker-Duocarmycin payload, Vc-seco-DUBA (Vc-seco-DUBA (HY-128957)), conjugated to an anti-B7-H3 humanized IgG1κ monoclonal antibody. Vobramitamab duocarmazine has antineoplastic activity.
Research Area：Cancer
Targets：Antibody-Drug Conjugates (ADCs)
Related Small Molecules:Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine;Enfortumab vedotin-ejfv;Sacituzumab govitecan;Belantamab mafodotin;Disitamab vedotin
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