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Dyrk1A/α-synuclein-IN-1
Biological Activity:Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual Dyrk1A and α-synuclein aggregation inhibitor with IC50 values of 177 nM and 10.5 µM, respectively. Dyrk1A/α-synuclein-IN-1 has high predictive CNS penetration and neuroprotective effect.
Research Area:Neurological Disease
Targets:DYRK
Related Small Molecules:Harmine hydrochloride;T025;ID-8;Dyrk1A-IN-2;GSK-626616;GNF2133 hydrochloride;ARN25068;Haspin-IN-1;LDN-192960 hydrochloride;CLK-IN-T3;GNF4877;DYRKs-IN-2;JH-XIV-68-3;DYRKs-IN-1 hydrochloride;Protein kinase inhibitors 1 hydrochloride;KH-CB20;Dyrk1A/α-synuclein-IN-2;AZ191;Woodtide;CK2/ERK8-IN-1;DYRK1-IN-1;Dyrk1A-IN-5;ML167;tBID;Dyrk1A-IN-4;Mirk-IN-1;Dyrk1A-IN-1
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