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Lidocaine

CAS No. : 137-58-6

Biological Activity：Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia^[2].

Research Area：Cancer|Cardiovascular Disease

Targets：MEK|NF-κB|Sodium Channel|Apoptosis|ERK

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