LEB-03-146

For research use only. We do not sell to patients.

LEB-03-146

Biological Activity:LEB-03-146 is a WEE1 DUBTAC (deubiquitinase-targeting chimera) linking AZD1775 (Adavosertib) to the OTUB1 recruiter EN523 through a PEG2 linker. LEB-03-146 shows significant WEE1 stabilization in HEP3B hepatoma cancer cells.

Research Area:Cancer

Targets:Wee1

Related Small Molecules:DB0614;LEB-03-153;WEE1-IN-4;LEB-03-145;PD0166285 dihydrochloride;WEE1-IN-3;RSS0680;WEE1-IN-5;Adavosertib;PD 407824;LEB-03-144

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