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GDC-0834

CAS No. : 1133432-49-1

Biological Activity：GDC-0834 is a potent and selective BTK inhibitor. GDC-0834 inhibits BTK with an in vitro IC₅₀ of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC₅₀ of 1.1 and 5.6 μM in mouse and rat, respectively.

Research Area：Inflammation/Immunology

Targets：Btk

Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Chemical Probe Library;Anti-Blood Cancer Compound Library;

Related Small Molecules:JAK3/BTK-IN-1;Elsubrutinib;ARQ 531;PF-06250112;PCI 29732;CHMFL-EGFR-202;Avitinib;RN486;GDC-0834 Racemate;Spebrutinib besylate;Vecabrutinib;BMX-IN-1;Tolebrutinib;BTK-IN-16;(R)-Zanubrutinib;Pirtobrutinib;CTA056;EGFR-IN-40;QL-X-138;ACP-5862;BTK-IN-12;JAK3/BTK-IN-4;JAK3/BTK-IN-6;BTK inhibitor 20;SJF620

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