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Kartogenin
CAS No. : 4727-31-5
Biological Activity：Kartogenin (KGN) is an inducer of differentiation of human mesenchymal stem cells into chondrocytes, with an EC50 of 100 nM. Kartogenin binds filamin A, disrupts its interaction with the transcription factor core-binding factor β subunit (CBFβ), and induces chondrogenesis by regulating the CBFβ-RUNX1 transcriptional program. Kartogenin can be used for the research of osteoarthritis (OA)[2].
Research Area：Inflammation/Immunology
Targets：TGF-beta/Smad
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Stem Cell Signaling Compound Library;TGF-beta/Smad Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Targeted Diversity Library;Anti-Liver Cancer Compound Library ;Osteogenesis Compound Library;
Related Small Molecules:TGFβ-IN-2;SRI-011381;Ponsegromab;Isoviolanthin;ALK5-IN-32;Asiaticoside;Halofuginone hydrobromide;ALK5-IN-28;Oxymatrine;Trabedersen;CCT365623 hydrochloride;Butaprost;Disitertide TFA;ALK5-IN-34;Alantolactone;(E)-SIS3;Chebulinic acid;R-268712;Mongersen;EMT inhibitor-1;IDE 2;10,11-Dehydrocurvularin
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