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Vinpocetine
CAS No. : 42971-09-5
Biological Activity：Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders[2][3].
Research Area：Inflammation/Immunology|Neurological Disease|Cardiovascular Disease|Cancer
Targets：Phosphodiesterase (PDE)|Sodium Channel|IKK
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