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FIT-039
CAS No. : 1113044-49-7
Biological Activity:FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
Research Area:Infection
Targets:HSV|CMV|DNA/RNA Synthesis|CDK
Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Antiviral Compound Library;Anti-Aging Compound Library;Orally Active Compound Library;Anti-Breast Cancer Compound Library;Anti-Blood Cancer Compound Library;Human Metabolite Library;Cancer Stem Cells Compound Library;
Related Small Molecules:DB0614;Isoborneol;pUL89 Endonuclease-IN-1;Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;Dinaciclib;Vidarabine monohydrate;SNS-032;CC-671;(E/Z)-Zotiraciclib;CDK1-IN-4;P1788;CCT-251921;BS-181;Samuraciclib hydrochloride hydrate;Thymidine-13C5,15N;NSC 617145;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;T025;6-Thio-2′-Deoxyguanosine;Flavopiridol
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