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Dihydrocapsaicin
CAS No. : 19408-84-5
Biological Activity：Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat[2][3].
Research Area：Neurological Disease|Cardiovascular Disease
Targets：Akt|Reactive Oxygen Species|TRP Channel|Bcl-2 Family|Caspase|Apoptosis|PI3K
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