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LBW242
CAS No. : 867324-12-7
Biological Activity：LBW242, a 3-mer and Smac mimetic, is a potent and orally active proapoptotic IAP inhibitor. LBW242 shows effects on mutant FLT3-expressing cells. LBW242 has activity against multiple myeloma, and potentiates TRAIL- and anticancer drug-mediated cell death of ovarian cancer cells[2].
Research Area：Cancer
Targets：FLT3|IAP
Related Small Molecules:AT9283;Xevinapant;(E/Z)-Zotiraciclib;Crotonoside;FLT3-IN-13;PDGFRα/FLT3-ITD-IN-2;FLT3/CDK4-IN-1;XIAP degrader-1;HP1142;ENMD-2076 Tartrate;MX69;ATH686;AZD2932;AKN-028 acetate;FLT3-IN-3;UNC2025 hydrochloride;Tandutinib;Gilteritinib-d8;PF 477736;(R)-3-Hydroxy Midostaurin;APG-1387;SBP-0636457;BSc5371;OTS447;PDGFRα/FLT3-ITD-IN-1;TAK-659 hydrochloride;GDC-0152
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