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AMG131
CAS No. : 315224-26-1
Biological Activity：AMG131 (INT131), a potent and highly selective PPARγ partial agonist, binds to PPARγ and displaces Rosiglitazone with a Ki of ~10 nM. AMG131 can be used for research of type-2 diabetes mellitus (T2DM)[2].
Research Area：Metabolic Disease
Targets：PPAR
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Anti-diabetic Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Lipid Metabolism Compound Library ;Antidepressant Compound Library;Nuclear Receptor Compound Library;Osteogenesis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Falcarindiol;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;PPARγ agonist 7;Licarin B;Mifobate;Daidzein-d4;Ciglitazone;MK-886;CP-775146;FK614;Muraglitazar;Magnolol;PPAR agonist 1;PPARα agonist 1;PPARγ phosphorylation inhibitor 1;GSK0660;Glabridin;CUDA;Norathyriol;Saroglitazar;GW 9578;Elafibranor;ST247;Bilobetin
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