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Ezatiostat
CAS No. : 168682-53-9
Biological Activity：Ezatiostat (TER199 free base; TLK199) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat has the potential for myelodysplastic syndrome (MDS) treatment[2].
Research Area：Cancer
Targets：Gutathione S-transferase|Apoptosis
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Peptidomimetic Library; Drug Repurposing Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Anti-COVID-19 Compound Library;Endoplasmic Reticulum Stress Compound Library;Orally Active Compound Library;Peptide Library;Cuproptosis Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10;Rigosertib sodium
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