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Dequalinium Chloride

CAS No. : 522-51-0

Biological Activity：Dequalinium Chloride is a selective blocker of apamin-sensitive K+ channels.
Target: Potassium Channel
Dequalinium Chloride is a selective blocker of apamin-sensitive K+ channels. Treatment with Dequalinium chloride did not influence conditions caused by haemolytic streptococci — verified by bacteriological examinations of pharyngeal smears — inspite of its efficiency in vitro [1]. Dequalinium chloride (DECA), a cationic, lipophilic mitochondrial poison, selectively targets the mitochondrial membrane of certain epithelial carcinoma cells, in which it inhibits cellular energy production. Higher DECA doses under either regimen induced severe toxic effects and mortality [2].

Research Area：Infection

Targets：Potassium Channel

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