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SAR502250
CAS No. : 503860-57-9
Biological Activity：SAR502250 is a potent, selective, ATP competitive, orally active and brain-penetrant inhibitor of GSK3, with an IC50 of 12 nM for human GSK-3β. SAR502250 displays antidepressant-like activity. SAR502250 can be used for the research of Alzheimer’s disease (AD)[2].
Research Area：Neurological Disease
Targets：GSK-3
Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;CNS-Penetrant Compound Library;Anti-Aging Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Anti-Alzheimer’s Disease Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Glucose Metabolism Compound Library;Antidepressant Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:TCS2002;AR-A014418;GSK 3 Inhibitor IX;MeBIO;Cromolyn-d5 sodium;GS87;ZDWX-25;ARN25068;PfGSK3/PfPK6-IN-2;RGB-286638;Laduviglusib (GMP);GSK3 Substrate, α, β subunit;DIF-3;Bikinin;A 1070722;Indirubin-3′-monoxime;Indirubin-5-sulfonate;Aloisine RP106;GNF4877;Indirubin-3′-monoxime-5-sulphonic acid;ABC1183;GSK-3β inhibitor 10;Cromolyn sodium;AZD1080;TCS 21311;KY19382;CHIR-98014;BRD0209;SB 415286
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