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Brexpiprazole S-oxide D8
Biological Activity:Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). Brexpiprazole is an atypical antipsychotic agent and a partial agonist of human 5-HT1A and dopamine receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM[2][3].
Research Area:Neurological Disease
Targets:Dopamine Receptor|5-HT Receptor
Related Small Molecules:F 13714;Alizapride hydrochloride;Thioproperazine;Mosapride-d5;Bromopride-d3;Nuciferine;Glaucine;Renzapride;SB-277011 dihydrochloride;LY 344864 racemate;Harmine hydrochloride;MIF-1 TFA;Valerenic acid;Arotinolol;Sulpiride;(Rac)-Razpipadon;Melitracen-d6 hydrochloride;Clebopride malate;WAY-100635;Nelotanserin;Flupentixol-d4 dihydrochloride
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