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SNAP 94847 hydrochloride
CAS No. : 1781934-47-1
Biological Activity：SNAP 94847 hydrochloride is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 hydrochloride binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters[3].
Research Area：Neurological Disease
Targets：MCHR1 (GPR24)
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Anti-Obesity Compound Library;Lipid Metabolism Compound Library ;Targeted Diversity Library;Human Metabolite Library;
Related Small Molecules:SB-568849;[Ala17]-MCH;AZD1979;ALB-127158(a);ATC0175;MCH(human, mouse, rat);BMS-819881;MCHR1 antagonist 1;MCHR1 antagonist 2;Ethyl linolenate;Melanin Concentrating Hormone, salmon;SNAP 94847;GW-803430;MCH-1 antagonist 1;NGD-4715;MCHR1 antagonist 3;TC-MCH 7c;Ac-hMCH(6-16)-NH2;Neuropeptide EI, rat;BMS-814580
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