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BAY-707
CAS No. : 2109805-96-9
Biological Activity：BAY-707 is a substrate-competitive, highly potent and selective inhibitor of MTH1(NUDT1) with an IC50 of 2.3 nM. BAY-707 has a good pharmacokinetic (PK) profile to other MTH1 compounds and is well-tolerated in mice, but shows a clear lack of in vitro or in vivo anticancer efficacy.
Research Area：Cancer
Targets：DNA/RNA Synthesis
Related Small Molecules:Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;P1788;Thymidine-13C5,15N;NSC 617145;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Antitumor agent-74;Risdiplam;TH287 hydrochloride;Direct Black 38;7-TFA-ap-7-Deaza-ddA;BCH001;NKP-1339;Fialuridine;2′-O-MOE-5-Me-rC;PTC299;2′-F-Bz-dC Phosphoramidite
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