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Anti-inflammatory agent 21

CAS No. : 2408836-40-6

Biological Activity：Anti-inflammatory agent 21 (compound 9o) is an orally active and low cytotoxic anti-inflammatory agent, with an IC₅₀ value of 0.76 μM for NO. Anti-inflammatory agent 21 acts via accumulation ROS and blocks the NF-κB/MAPK signaling pathway. Anti-inflammatory agent 21 can ameliorate cartilage destruction and inflammatory cell infiltration in arthritis rats model.

Research Area：Inflammation/Immunology

Targets：NF-κB|Reactive Oxygen Species|NO Synthase

Related Small Molecules:Carboxy-PTIO potassium;D-α-Hydroxyglutaric acid disodium;Akt/NF-κB/JNK-IN-1;Chitoheptaose heptahydrochloride;Valeriandoid F;Icariside F2;N-Acetyl-D-cysteine;IKKγ NBD Inhibitory Peptide TFA;Topoisomerase I/II inhibitor 3;Ciwujianoside C3;CYPMPO;Mangiferin;Antioxidant agent-5;ALPK1-IN-1;NOS-IN-3;Regaloside A;IMD-ferulic;SN52;ROS-ERS inducer 1;Glucosamine-13C hydrochloride;L-Ascorbic acid sodium salt;D-Isofloridoside;5-Aminosalicylic Acid-D3 hydrochloride;L-Carnitine-d3 hydrochloride;Ginsenoside Rg1;Echinulin;Aminopicoline;Licochalcone D;QNZ

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