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Atabecestat
CAS No. : 1200493-78-2
Biological Activity：Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. Atabecestat s tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat has the potential for Alzheimer’s Disease treatment.
Research Area：Neurological Disease
Targets：Beta-secretase
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Neuronal Signaling Compound Library;Clinical Compound Library;CNS-Penetrant Compound Library;Orally Active Compound Library;Anti-Alzheimer’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;
Related Small Molecules:LY2886721;BACE1-IN-9;β-Secretase Inhibitor II;Cassiaside;Glabrolide;OM99-2;JNJ-67569762;β-Secretase Inhibitor III;BACE1-IN-12;BACE1-IN-11;Multitarget AD inhibitor-1;BACE-1 inhibitor 1;BACE1-IN-8;AM-6494;LX2343;LY2811376;COX-2-IN-22;AZD3839 free base;Aloenin;β-Secretase Inhibitor IV;AChE/BChE/BACE-1-IN-2;BACE1-IN-4;Sophoflavescenol;Aloeresin D;BACE-IN-1;BACE-1 inhibitor 2;Epiberberine chloride;BACE1-IN-2
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