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Aphidicolin

CAS No. : 38966-21-1

Biological Activity：Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line^[2]^[3].

Research Area：Infection|Inflammation/Immunology

Targets：HSV|Orthopoxvirus|DNA/RNA Synthesis|Antibiotic|Apoptosis

Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;

Related Small Molecules:Physalin A;Bomedemstat ditosylate;Sandramycin;Enpp/Carbonic anhydrase-IN-1;Isoborneol;GK563;Calpeptin;Oritavancin;Lobetyolin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Leucomycin;Ametantrone;BJE6-106;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;Vidarabine monohydrate

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