For research use only. We do not sell to patients.
Tanespimycin
CAS No. : 75747-14-7
Biological Activity：Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90[5]. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression[3].
Research Area：Cancer|Infection
Targets：Autophagy|HSP|Mitophagy|Bacterial|Antibiotic|Apoptosis
Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Macrocyclic Compound Library;Antibacterial Compound Library;Endoplasmic Reticulum Stress Compound Library;Pyroptosis Compound Library;Cytoskeleton Compound Library;Antibiotics Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Mitochondria-Targeted Compound Library;Rare Diseases Drug Library;Anti-Prostate Cancer Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Sandramycin;LLO (91-99);Gepotidacin;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Oritavancin;Lobetyolin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;BJE6-106;Dinaciclib;Antibacterial agent 99;Ecteinascidin 770;MDM2-p53-IN-15
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
