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Hydroxy-Dynasore
CAS No. : 1256493-34-1
Biological Activity:Hydroxy Dynasore (Dyngo-4a), a structural analog of Dynasore (HY-15304), is an potency improved, low cytotoxicity and non‐specific binding dynamin inhibitor with IC50 values of 0.38 μM and 2.3 μM for brain dynamin I and recombinant rat dynamin II, respectively. Hydroxy Dynasore inhibits dynamin‐dependent endocytosis of transferrin with an IC50 of 5.7 μM in vitro.
Research Area:Neurological Disease
Targets:Dynamin
Related Screening Libraries:Bioactive Compound Library Plus;Cytoskeleton Compound Library;
Related Small Molecules:Dynole 34-2;Schaftoside;Dynamin inhibitory peptide TFA;DynaMin inhibitory peptide, myristoylated;Drp1-IN-1;Dynole 2−24;Mdivi-1;Dynasore
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