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Ac-FLTD-CMK

CAS No. : 2376255-48-8

Biological Activity：Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC₅₀ of 46.7 nM), caspases-4 (IC₅₀ of 1.49 μM), caspases-5 (IC₅₀ of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3.

Research Area：Inflammation/Immunology

Targets：Pyroptosis|Caspase

Related Screening Libraries:Bioactive Compound Library Plus;

Related Small Molecules:Dehydrocorydaline;Z-DEVD-AMC;p-nitro-Pifithrin-α;ML132;Ac-FEID-CMK TFA;L67;AKN-028 acetate;Ossirene;δ-Secretase inhibitor 11;Anticancer agent 63;Fenbufen-d9;Penicillic acid;Sesamolin;PI-1840;5,7-Dihydroxychromone;HDAC1-IN-5;Ac-DEVD-pNA;Crustecdysone;Caspase-3-IN-1;PARP-1-IN-2;Z-WEHD-FMK;Mca-YVADAP-Lys(Dnp)-OH;Aspirin;BOC-D-FMK;Ac-LEHD-AFC;Asperosaponin VI

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