AMI-1 free acid

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AMI-1 free acid

CAS No. : 134-47-4

Biological Activity:AMI-1 free acid is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8.8 μM and 3.0 μM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 free acid exerts PRMTs inhibitory effects by blocking peptide-substrate binding.

Research Area:Cancer

Targets:Histone Methyltransferase

Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Covalent Screening Library;Reprogramming Compound Library;Anti-Blood Cancer Compound Library;Human Metabolite Library;

Related Small Molecules:EEDi-5285;EZH2-IN-2;BIX-01294;SGC707;(S)-HH2853;G9a-IN-1;UNC4976;MS1943;OTS186935 hydrochloride;MS8815;(R)-HH2853;EPZ020411;Furamidine dihydrochloride;EZH2-IN-12;UNC0642;MU1656;Chaetocin;UNC0646;UNC0224;MRK-740;SMYD2-IN-1;PRMT5-IN-21;Sinefungin;MM-401;SETDB1-TTD-IN-1;Dot1L-IN-2;PRMT5-IN-10;PRMT1-IN-1

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