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TSPO Ligand-Linker Conjugates 1
Biological Activity：TSPO Ligand-Linker Conjugates 1 contains a ligand for translocator protein (TSPO) and a linker, which is used for the synthesis of mitochondria-targeting autophagy-targeting chimera (AUTAC). AUTAC can bind the TSPO on the outer mitochondrial membrane (OMM) of mitochondria and degrades impaired mitochondria and proteins via mitophagy, and improves mitochondrial activity. TSPO Ligand-Linker Conjugates 1 can be used in mitochondrial dysfunction related research, including neurodegenerative diseases, cancer, and diabetes.
Research Area：Cancer|Metabolic Disease|Neurological Disease
Targets：AUTACs|Mitophagy
Related Small Molecules:Curcumin;TSPO ligand-2;Melatonin-d3;Resveratrol;Clioquinol;TSPO ligand-3;Betulinic acid;Matrine;Sulfosuccinimidyl oleate;Hemin;Polydatin;AICAR;ABT 737-d8;Parthenolide;D-Glutamine;Aspirin;Salicylic acid-d6
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