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NVS-CECR2-1
CAS No. : 1992047-61-6
Biological Activity：NVS-CECR2-1, a non-BET family Bromodomain (BRD) inhibitor, is a potent and selective cat eye syndrome chromosome region, candidate 2 (CECR2) inhibitor. NVS-CECR2-1 binds to CECR2 BRD with high affinity (IC50=47 nM; KD=80 nM). NVS-CECR2-1 exhibits cytotoxic activity and induces apoptosis against various cancer cells by targeting CECR2 as well as via CECR2-independent mechanism.
Research Area：Cancer
Targets：Epigenetic Reader Domain|Apoptosis
Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Reprogramming Compound Library;Chemical Probe Library;Anti-Blood Cancer Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;RVX-297;Lobetyolin;BRD4 Inhibitor-19;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;UNC6349 (Ket2);Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib
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