Polyinosinic-polycytidylic acid sodium

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Polyinosinic-polycytidylic acid sodium

CAS No. : 42424-50-0

Biological Activity:Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis[2].

Research Area:Cancer|Inflammation/Immunology

Targets:Toll-like Receptor (TLR)|Apoptosis

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