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DNA-PK-IN-5

CAS No. : 2719736-43-1

Biological Activity：DNA-PK-IN-5 is a potent inhibitor of DNA-PK. DNA-PK-IN-5 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-5 enhances the sensitivity of tumor tissues to radiotherapy, overcomes the problem of drug resistance, and enhances the inhibitory effect on a variety of solid tumors and hematological tumors (extracted from patent WO2021204111A1, compound 2).

Research Area：Cancer

Targets：DNA-PK

Related Small Molecules:PI-103-d8;PI-103 Hydrochloride;SF2523;BAY-8400;DNA-PK-IN-6;Torin 2;NU 7026;PIK-90;PIK-75;(R)-VX-984;LY294002 hydrochloride;CC-115;DNA-PK-IN-4;AMA-37;DNA-PK-IN-7;KU-57788;DNA-PK-IN-9;NU5455;Samotolisib;DNA-PK-IN-1;VX-984;ATR-IN-15;DNA-PK-IN-3;IC 86621;YU238259;Compound 401

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