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6-Demethoxytangeretin
CAS No. : 6601-66-7
Biological Activity：6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus reticulata. 6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase (ALK) and mitogen-activated protein kinase (MAPK) pathways. 6-Demethoxytangeretin facilitates the CRE-mediated transcription associated with learning and memory in cultured hippocampal neurons[2].
Research Area：Cancer|Inflammation/Immunology|Neurological Disease
Targets：Anaplastic lymphoma kinase (ALK)
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Natural Product Library;Anti-Cancer Compound Library;Lipid Compound Library;Medicine Food Homology Compound Library;Traditional Chinese Medicine Active Compound Library;Flavonoids Library;Anti-Blood Cancer Compound Library;Food-Sourced Compound Library ;Anti-Cancer Natural Product Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;Human Metabolite Library;
Related Small Molecules:ALK-IN-9;KRCA-0008;Alectinib-d8;MS4078;TL13-22;NVP-TAE 684;ALK5-IN-30;TL13-112;ALK-IN-22;Alectinib;ALK-IN-12;Entrectinib;ALK kinase inhibitor-1;WY-135;TL13-110;ALK inhibitor 1;Envonalkib;GSK1838705A;RIPK2-IN-1;CJ-2360;ALK-IN-1;ALK5-IN-29;X-376;ALK-IN-21;Repotrectinib;Lorlatinib;M4K2234;MS4077
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