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Jervine
CAS No. : 469-59-0
Biological Activity：Jervine (11-Ketocyclopamine) is a potent Hedgehog (Hh) inhibitor with an IC50 of 500-700 nM. Jervine is a natural teratogenic sterodial alkaloid from rhizomes of Veratrum nigrum. Jervine has anti-inflammatory and antioxidant properties[2].
Research Area：Cancer|Inflammation/Immunology
Targets：Smo|Hedgehog
Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Natural Product Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Traditional Chinese Medicine Active Compound Library;Alkaloids Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Cancer Natural Product Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Saikosaponin B1;MRT-10;LEQ506;RU-SKI 43;Dynarrestin;RL-0070933;20(S)-Hydroxycholesterol;Sonidegib;PF-5274857 hydrochloride;SANT 2;MRT-83 hydrochloride;Ciliobrevin D;TPB15;CUR61414;HSP70-IN-3;SANT-1;Hh-Ag1.5;SAG-d3;SMANT hydrochloride;Robotnikinin;Ciliobrevin A;BMS-833923;SMO-IN-2
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