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Thioridazine-d3 2-Sulfone

CAS No. : 1329652-09-6

Biological Activity：Thioridazine-d3 2-Sulfone is the deuterium labeled Thioridazine hydrochloride. Thioridazine hydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine hydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine hydrochloride shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs)^[2]^[3]^[4].

Research Area：Cancer|Infection|Neurological Disease

Targets：Dopamine Receptor|5-HT Receptor|Autophagy|Bacterial|Apoptosis

Related Small Molecules:Physalin A;Bomedemstat ditosylate;F 13714;Sandramycin;LLO (91-99);Gepotidacin;Enpp/Carbonic anhydrase-IN-1;Alizapride hydrochloride;GK563;Calpeptin;Thioproperazine;Oritavancin;Lobetyolin;Azlocillin sodium salt;Mosapride-d5;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin

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