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SAR405838
CAS No. : 1303607-60-4
Biological Activity：SAR405838 (MI-77301), an analog of MI-773, is a highly potent and selective MDM2-p53 interaction inhibitor. SAR405838 binds to MDM2 with a Ki of 0.88 nM. SAR405838 induces apoptosis and has potent antitumor activity[2].
Research Area：Cancer
Targets：MDM-2/p53|Apoptosis|E1/E2/E3 Enzyme
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Oxygen Sensing Compound Library;Ubiquitination Compound Library;Ferroptosis Compound Library;Pyroptosis Compound Library;Chemical Probe Library;Glutamine Metabolism Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Protein-protein Interaction Inhibitor Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;UBE2T/FANCL-IN-1;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D
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