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Brompheniramine

CAS No. : 86-22-6

Biological Activity：Brompheniramine ((±)-Brompheniramine) is a potent and orally active antihistamine of the alkylamine class. Brompheniramine is a selective histamine H1 receptor antagonist with a K_d of 6.06 nM. Brompheniramine can block the hERG channels, calcium channels, and sodium channels with IC₅₀s of 0.90 μM, 16.12 μM and 21.26 μM, respectively. Brompheniramine has anticholinergic, antidepressant and anesthetic properties and can be used for allergic rhinitis research^[2]^[3]^[4].

Research Area：Endocrinology|Inflammation/Immunology|Neurological Disease

Targets：Calcium Channel|mAChR|Histamine Receptor|Sodium Channel|Potassium Channel

Related Small Molecules:VU0357017 hydrochloride;Benidipine hydrochloride;Lu AE98134;CaV1.3 antagonist-1;14-Deoxyandrographolide;TBPB;Kv3 modulator 2;Imidafenacin;Zandatrigine;Sabcomeline;(Rac)-MEM 1003;Tripelennamine;Glaucine;Veratridine;MK-6884;Efonidipine hydrochloride monoethanolate;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;Pinacidil;MRS 1523;GX-674

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