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BRD9185
CAS No. : 2057420-29-6
Biological Activity:BRD9185 is a Dihydroorotate dehydrogenase (DHODH) inhibitor, with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro and is curative after just three doses in a P. berghei mouse model.
Research Area:Infection
Targets:Parasite|Dihydroorotate Dehydrogenase|DNA/RNA Synthesis
Related Small Molecules:(+)-Isopulegol;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;SQ109;Trypanothione synthetase-IN-3;P1788;Pyrantel;α-Terpinene;Dehydrocorydaline;Thymidine-13C5,15N;NSC 617145;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;Niclosamide monohydrate;Febrifugine dihydrochloride;6-Thio-2′-Deoxyguanosine
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