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Cap-dependent endonuclease-IN-2
Biological Activity：Cap-dependent endonuclease-IN-2 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-2 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-2 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent WO2019052565A1, compound 28).
Research Area：Infection
Targets：Influenza Virus
Related Small Molecules:Curcumin;(R)-Camptothecin-d5;Glaucine;Hypericin;Neuraminidase-IN-3;FGI-106 tetrahydrochloride;Molnupiravir;Onradivir;SP187;Nuezhenidic acid;Ketotifen fumarate;Baloxavir-d5;Coptisine chloride;Ginsenoside Rb2;T-1105;Tetrahydroepiberberine;JNJ4796;Loratadine-d5;Camptothecin;Eriodictyol;Catechin-13C3;Dendrobine;N-Glycolylneuraminic acid;Clovamide;Influenza A NP(366-374) Strain A/PR/8/35;Rose Bengal sodium;Psoralen
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