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Sigma-1 receptor antagonist 1
CAS No. : 1639220-19-1
Biological Activity：Sigma‑1 receptor antagonist 1 (compound 137) is a potent and selective sigma-1 receptor (σ1R) antagonist, with a high binding affinity to σ1R receptor (Ki = 1.06 nM). Sigma‑1 receptor antagonist 1 exhibits antineuropathic pain activity and acts as a promising agent for the treatment of neuropathic pain.
Research Area：Neurological Disease
Targets：Sigma Receptor
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:BD1063 dhydrochloride;Phenyltoloxamine;E1R;EST73502;(±)-Vesamicol hydrochloride;Sigma-LIGAND-1;BMY-14802 hydrochloride;SKF 83959 hydrobromide;Pentoxyverine;SR-31747 free base;Antidepressant agent 3;PD 144418;EST64454 hydrochloride;Glycerol phenylbutyrate-d5;Rimcazole dihydrochloride;Siramesine hydrochloride;Antidepressant agent 4;OPC-14523 hydrochloride;NE-100 hydrochloride;Blarcamesine;DuP 734;Panamesine
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