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8-M-PDOT
CAS No. : 134865-70-6
Biological Activity：8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. 8-M-PDOT is 5.2-fold selective for MT2 over MT1 receptors. 8-M-PDOT binds human recombinant MT2 and MT2 receptors with pKi values of 8.23 and 8.95 respectively. 8-M-PDOT has anxiolytic-like activity[2].
Research Area：Neurological Disease
Targets：Melatonin Receptor
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Targeted Diversity Library;
Related Small Molecules:Melatonin-d3;Antidepressant agent 3;6-Chloromelatonin;DH97;TIK-301;N-Acetyltryptamine;Luzindole;ACH-000143;Antidepressant agent 4;Agomelatin-d3;UCM 608;4-P-PDOT;Piromelatine;S26131;Melatonin-d7;2-Iodomelatonin
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