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T-2513
CAS No. : 288247-87-0
Biological Activity:T-2513 is a selective topoisomerase I inhibitor. T-2513 binds covalently to and stabilizes the topoisomerase I-DNA complex and inhibits DNA replication and RNA synthesis, ultimately leading to cell death.
Research Area:Cancer
Targets:Topoisomerase|DNA/RNA Synthesis
Related Small Molecules:Gepotidacin;Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;Topoisomerase I/II inhibitor 3;(R)-Camptothecin-d5;P1788;Thymidine-13C5,15N;NSC 617145;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Topoisomerase II inhibitor 8;Antitumor agent-74;FLT3-IN-13;Risdiplam;TH287 hydrochloride;TP3011;Direct Black 38;TAS-103 dihydrochloride
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