Macitentan (n-butyl analogue)

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Macitentan (n-butyl analogue)

CAS No. : 556797-16-1

Biological Activity:Macitentan n-butyl analogue is a n-butyl analogue of Macitentan. Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).

Research Area:Cardiovascular Disease|Endocrinology

Targets:Endothelin Receptor

Related Small Molecules:BQ-788;[Asn18] Endothelin-1, human;Endothelin-3, human, mouse, rabbit, rat TFA;IRL 2500;Sarafotoxin S6c;Sarafotoxin S6a;ANP (1-30), frog;IRL-1620 TFA;Tezosentan;ACT-373898;Ro 46-2005;Ro 46-8443;[Ala2] Endothelin-3, human;ZD-1611;PD-159020;Aminaftone;Aprocitentan-d4;Endothelin 1 (swine, human);Atrial Natriuretic Peptide (ANP) (1-28), rat;Carperitide acetate;[Ala1,​3,​11,​15]​-​Endothelin (53-63) (TFA);Sparsentan-d5;BQ-123 TFA

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