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EB-47 dihydrochloride

CAS No. : 1190332-25-2

Biological Activity：EB-47 dihydrochloride, a potent and selective PARP-1/ARTD-1 inhibitor with an IC₅₀ value of 45 nM, shows modest potency against ARTD5 with an IC₅₀ value of 410 nM. EB-47 mimics the substrate NAD⁺ and extends from the nicotinamide to the adenosine subsite.

Research Area：Inflammation/Immunology

Targets：PARP

Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Immunology/Inflammation Compound Library;Anti-Aging Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;

Related Small Molecules:Rucaparib monocamsylate;AZD-2461;Senaparib;Dehydrocorydaline;Rucaparib hydrochloride;Niraparib tosylate;G007-LK;PROTAC PARP1 degrader;UPF 1069;DP-C-4;Δ5-Avenasterol-d4;PARP14 inhibitor H10;CEP-9722;E7449;PARP1-IN-11;PI-1840;5,7-Dihydroxychromone;PARP-1/2-IN-1;(8R,9S)-Talazoparib;3-Aminobenzamide;PARP1-IN-12;PARP-1-IN-2;BRCA1-IN-1;NMS-P118;VPC-70063;G244-LM

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